William Oldham

Principal Investigator

Associate Professor of Medicine and Director of Research and Innovation for Pulmonary, Critical Care and Sleep Medicine. Studies cell metabolism in pulmonary vascular and fibrotic lung disease.

Education and Training

Research Fellow, Pulmonary and Critical Care Medicine 2012–2015 Brigham and Women’s Hospital and Harvard Medical School

Clinical Fellow, Pulmonary and Critical Care Medicine 2010–2014 Harvard Combined Pulmonary and Critical Care Fellowship

Resident, Internal Medicine 2008–2010 Massachusetts General Hospital

MD 2008 Vanderbilt University School of Medicine

PhD in Pharmacology 2006 Vanderbilt University

BS in Chemistry with Honors 2001 University of North Carolina at Chapel Hill

Will came to lung disease by way of structural pharmacology. He trained in the Medical Scientist Training Program at Vanderbilt University, where his doctoral work with Heidi Hamm addressed the mechanism by which receptors activate heterotrimeric G proteins. He moved to Boston for residency in internal medicine at Massachusetts General Hospital and for fellowship in the Harvard Combined Pulmonary and Critical Care program, where his clinical research used invasive cardiopulmonary exercise testing to characterize unexplained exertional dyspnea. He began working on cell metabolism during a research fellowship with Joseph Loscalzo at Brigham and Women’s Hospital, and started his own laboratory in 2015. He moved the laboratory to Brown University Health in June 2025, where he is an attending physician in pulmonary and critical care medicine.